Description

L-2-Aminobutanol-D5 is a deuterium-labeled isotopologue of L-2-Aminobutanol, a chiral amino alcohol. This compound is a critical stable isotope-labeled standard used for precise quantification and metabolic pathway tracing in advanced analytical research. It is essential for professionals in pharmaceutical development, metabolomics, and biochemical research who require high-purity, isotopically enriched materials for internal standards and tracer studies.

Application

• Internal Standard for LC-MS/MS and GC-MS: Used for the accurate quantification of L-2-Aminobutanol and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to elucidate metabolic routes and rates.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and method validation in API development.
• Biochemical Research: Utilized in enzymatic and receptor-binding studies where a non-radioactive, traceable label is required.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-precision analytical techniques for clinical diagnostics and environmental analysis.
• Synthesis of Labeled Compounds: Acts as a chiral building block for the synthesis of more complex deuterium-labeled pharmaceuticals and biochemical probes.

Basic Information

Item	Detail
Product Name	L-2-Aminobutanol-D5
CAS No.	1217783-40-8
Molecular Formula	C4H6D5NO
Molecular Weight	94.16 g/mol (approx.)
Synonyms	(2S)-2-Aminobutan-1-ol-D5; L-2-Amino-1-butanol-D5; (S)-2-Aminobutanol-D5; L-Threoninol-D5 (deuterated); (S)-2-Amino-1-butanol-D5; 1-Butanol, 2-amino-, (2S)-, pentadeuterio-; Stable Isotope Labeled L-2-Aminobutanol
EINECS	Contact for details

Quality Control

Our L-2-Aminobutanol-D5 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-content), chemical purity, and chiral purity. We adhere to relevant standards for high-purity reference materials, and custom synthesis to specific purity or enrichment levels is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.