Description

(3S)-3-(2,3,4,5,6-Pentadeuteriophenyl)-3-[4-(Trifluoromethyl)Phenoxy]Propan-1-Amine is a high-purity, deuterium-labeled organic compound designed for advanced research and development applications. This compound is critical for studies requiring precise metabolic and pharmacokinetic tracking due to its isotopic labeling, offering enhanced analytical sensitivity and stability. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions engaged in drug discovery and development. Our supply ensures consistent quality and reliability for your most demanding synthetic and analytical workflows.

Application

• Pharmaceutical Reference Standard: Serves as a certified internal standard for the quantitative bioanalysis of its non-deuterated counterpart in complex biological matrices using LC-MS/MS.
• Metabolic Pathway Tracing: Enables detailed investigation of drug metabolism, absorption, distribution, and excretion (ADME) studies in preclinical research.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high-accuracy quantification in analytical method development and validation for regulatory submissions.
• Mechanistic Biochemical Research: Used as a tool to study enzyme mechanisms and receptor binding interactions without interference from background signals.
• Deuterated Building Block: Acts as a specialized synthon for the synthesis of more complex deuterium-labeled molecules for research purposes.

Basic Information

Product Name	(3S)-3-(2,3,4,5,6-Pentadeuteriophenyl)-3-[4-(Trifluoromethyl)Phenoxy]Propan-1-Amine
CAS No.	1217770-71-2
Molecular Formula	C₁₆H₁₀D₅F₃NO
Molecular Weight	313.33 g/mol (for the deuterated form)
Synonyms	(3S)-3-(Perdeuteriophenyl)-3-[4-(trifluoromethyl)phenoxy]propan-1-amine; (S)-3-(2,3,4,5,6-Pentadeuteriophenyl)-3-(4-(trifluoromethyl)phenoxy)propan-1-amine; d5-Fluoxetine metabolite derivative; Deuterated Fluoxetine analog; 1-Amino-3-((4-(trifluoromethyl)phenoxy)-3-(pentadeuteriophenyl)propane (S-isomer); (S)-3-(Perdeuterophenyl)-3-(4-trifluoromethylphenoxy)propylamine
EINECS	Contact for details

Quality Control

Every batch of (3S)-3-(2,3,4,5,6-Pentadeuteriophenyl)-3-[4-(Trifluoromethyl)Phenoxy]Propan-1-Amine is manufactured under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments, including deuterium enrichment (D%) verification and chiral purity confirmation. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Deuterium Enrichment (MS)	≥ 95 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.