Description

1,2,2,6-Tetradeuterio-3-Methyl-6-Propan-2-Ylcyclohexan-1-Ol is a deuterated derivative of menthol, a compound of significant interest in advanced chemical research and development. This isotopically labeled compound is essential for applications requiring precise molecular tracking and analysis, such as in metabolic and pharmacokinetic studies. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories engaged in the development of deuterated drugs, NMR spectroscopy, and mass spectrometry.

Application

• Deuterated Pharmaceutical Intermediates: Serves as a key building block in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) for improved metabolic stability and bioavailability.
• NMR Spectroscopy: Used as an internal standard or a probe in Nuclear Magnetic Resonance (NMR) studies due to its distinct spectral properties, aiding in structural elucidation and reaction monitoring.
• Mass Spectrometry Standards: Employed as a stable isotope-labeled internal standard in LC-MS and GC-MS for accurate quantitative analysis in complex biological matrices.
• Metabolic Pathway Tracing: Facilitates the study of drug metabolism and biochemical pathways in pharmacological and toxicological research.
• Fragrance and Flavor Research: Used in advanced research to understand the metabolism and stability of flavor compounds like menthol.
• Chemical Reaction Mechanism Studies: Acts as a tracer in mechanistic studies to investigate reaction pathways and kinetics in organic synthesis.

Basic Information

Product Name	1,2,2,6-Tetradeuterio-3-Methyl-6-Propan-2-Ylcyclohexan-1-Ol
CAS No.	1217765-02-0
Molecular Formula	C10H16D4O
Molecular Weight	158.28 g/mol
Synonyms	Deuterated Menthol; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexan-1-ol-2,2,6,6-d4; d4-Menthol; 1,2,2,6-Tetradeuterio-5-methyl-2-(1-methylethyl)cyclohexanol; (1R,2S,5R)-1,2,2,6-Tetradeuterio-3-Methyl-6-(1-Methylethyl)cyclohexanol; Hexahydrothymol-d4; 3-p-Menthanol-d4; Menthol (ring-2,2,6,6-d4)
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR, MS, and HPLC. Certificates of Analysis (COA) are provided, detailing parameters such as chemical purity, isotopic enrichment (atom % D), and identity confirmation. We adhere to relevant industry standards for research chemicals, ensuring reliable and consistent material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.