Description

Trans 1-Benzyl-4-(4-Fluorophenyl)-3-Piperidinemethanol-D4 is a high-purity, deuterated organic compound primarily used as a critical intermediate in pharmaceutical research and development. Its value lies in its role as a stable isotope-labeled analog, essential for advanced pharmacokinetic, metabolic, and bioanalytical studies. This compound is specifically needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors working on novel drug discovery programs, particularly those involving neurological or psychiatric targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) for improved metabolic stability.
• Metabolic Research: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification of parent compounds in biological matrices.
• Drug Discovery & Development: Employed in preclinical and clinical studies to track drug absorption, distribution, metabolism, and excretion (ADME) using isotope tracing techniques.
• Neurological & Psychiatric Agent Synthesis: Serves as a precursor in the development of deuterated analogs of compounds targeting central nervous system disorders.
• Isotope Labeling: Provides a source of deuterium atoms for the preparation of labeled compounds used in mechanistic studies and patent strategies.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	Trans 1-Benzyl-4-(4-Fluorophenyl)-3-Piperidinemethanol-D4
CAS No.	1217676-35-1
Molecular Formula	C19H18D4FNO
Molecular Weight	299.41 g/mol
Synonyms	1-Benzyl-4-(4-fluorophenyl)-3-piperidinemethanol-d4; 3-Piperidinemethanol, 1-benzyl-4-(4-fluorophenyl)-, (3R-trans)-d4; (3R-trans)-1-Benzyl-4-(4-fluorophenyl)-3-piperidinemethanol-d4; Deuterated Benfluorex Metabolite Intermediate; D4-Labeled 1-Benzyl-4-(4-fluorophenyl)-3-piperidinemethanol; trans-1-Benzyl-4-(4-fluorophenyl)-3-hydroxymethylpiperidine-d4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical use. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) are provided, detailing batch-specific results for purity, assay, and deuterium incorporation. We adhere to cGMP principles where applicable to support our global clientele in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.