Description

(R)-(1-Mercaptomethyl-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester is a high-purity chiral building block and key intermediate in advanced pharmaceutical synthesis. Its value lies in providing a protected thiol and amine functionality, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors, enzyme inhibitors, and other small-molecule drugs.
• Peptidomimetics Research: Used in the design and construction of peptide analogs and mimetics where the (R)-configuration and protected thiol group are required.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Employed in the development of activity-based probes and molecular tools for studying biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• API Development: Integral to the research and process development stages of new chemical entities (NCEs) requiring a specific stereocenter.

Basic Information

Product Name	(R)-(1-Mercaptomethyl-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1217604-63-1
Molecular Formula	C15H23NO2S
Molecular Weight	281.41 g/mol
Synonyms	(R)-tert-Butyl (1-mercaptomethyl-2-phenylethyl)carbamate; (R)-N-Boc-1-amino-2-phenyl-3-propanethiol; Boc-Cys(Ph)-OH tert-butyl ester (incorrect but common search variant); (R)-N-(tert-Butoxycarbonyl)-2-phenylcysteamine; (R)-2-Phenyl-N-Boc-cysteamine; (R)-Boc-Cys(Ph)-ol; (R)-1-Mercaptomethyl-2-phenylethylcarbamic acid tert-butyl ester; tert-Butyl N-[(2R)-1-mercaptomethyl-2-phenylethyl]carbamate
EINECS	Contact for details

Quality Control

Our production of (R)-(1-Mercaptomethyl-2-Phenyl-Ethyl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We operate under a quality management system and can supply material suitable for research and development under current Good Manufacturing Practice (cGMP) guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the certificate of analysis. This compound is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.