Description

(R)-3-Azido-1-Phenyl-1-(2-Methylphenoxy-D7)Propane is a high-purity, deuterated azido compound designed for advanced research and development. This specialized building block is critical for applications requiring isotopic labeling, particularly in the synthesis of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and biotechnology industries for drug discovery, metabolic studies, and the development of diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets.
• Isotope Labeling: The incorporation of deuterium (D7) atoms makes it invaluable for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies, improving metabolic stability.
• Click Chemistry: The azido functional group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer chemistry.
• Agrochemical Research: Used in the synthesis of novel, labeled pesticide and herbicide candidates for environmental fate and metabolism studies.
• Biomolecular Probes: Serves as a precursor for creating labeled probes and tracers used in imaging and diagnostic assays.
• Academic & Institutional Research: Employed in university and government labs for fundamental studies in organic synthesis, catalysis, and medicinal chemistry.

Basic Information

Product Name	(R)-3-Azido-1-Phenyl-1-(2-Methylphenoxy-D7)Propane
CAS No.	1217603-70-7
Molecular Formula	C₁₆H₁₁D₇N₃O
Molecular Weight	~269.38 g/mol
Synonyms	(R)-3-Azido-1-phenyl-1-[(2-methyl-d7)phenoxy]propane; 1-Phenyl-1-[(2-methyl-d7)phenoxy]-3-azidopropane, (R)-; (R)-1-Phenyl-1-(2-methylphenoxy-D7)-3-azidopropane; Deuterated (R)-3-Azido-1-phenyl-1-(o-cresyloxy)propane; Azido-D7 Propane Derivative; (R)-D7-Azido Phenyl Propane Ether
EINECS	Contact for details

Quality Control

Every batch of (R)-3-Azido-1-Phenyl-1-(2-Methylphenoxy-D7)Propane is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and isotopic enrichment meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and deuterium content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Deuterium Content (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.