Description

(8S)-5,6,7,8-Tetrahydro-8-indolizinemethanamine is a chiral, saturated indolizine derivative that serves as a sophisticated building block in advanced organic synthesis. This compound is valued for its unique bicyclic scaffold and stereogenic center, which are critical for modulating biological activity and physicochemical properties in target molecules. It is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including potential therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Building block for creating novel pesticides and herbicides, leveraging its complex heterocyclic structure for enhanced target specificity.
• Chemical Biology Probe: Used in medicinal chemistry to explore structure-activity relationships (SAR) and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Asymmetric Catalysis Ligand Precursor: Potential starting material for the synthesis of chiral ligands used in enantioselective catalytic processes.
• Advanced Material Synthesis: Intermediate in the preparation of specialized organic compounds for electronic or optical materials research.

Basic Information

Product Name	(8S)-5,6,7,8-Tetrahydro-8-indolizinemethanamine
CAS No.	1217602-14-6
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	8-Indolizinemethanamine, 5,6,7,8-tetrahydro-, (8S)-; (8S)-5,6,7,8-Tetrahydro-8-indolizinemethanamine; (S)-5,6,7,8-Tetrahydro-8-indolizinemethanamine; (S)-8-(Aminomethyl)-5,6,7,8-tetrahydroindolizine; 1217602-14-6; (8S)-8-(Aminomethyl)-5,6,7,8-tetrahydroindolizine
EINECS	Contact for details

Quality Control

Our production of (8S)-5,6,7,8-Tetrahydro-8-indolizinemethanamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.