Description

3-(5-Methyl-1,2,4-Oxadiazol-3-Yl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require precise and reliable intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the 1,2,4-oxadiazole heterocycle, which is associated with diverse biological activities.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient palladium-catalyzed coupling with aryl or vinyl halides to create biaryl structures, a fundamental transformation in medicinal and process chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the oxadiazole moiety for bioactivity.
• Material Science & OLED Development: Serves as a building block for creating organic electronic materials, such as charge-transport layers or emissive materials in organic light-emitting diodes (OLEDs).
• Ligand Synthesis for Catalysis: Can be utilized to synthesize novel bidentate or tridentate ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and sensors that target specific biological processes or structures.

Basic Information

Product Name	3-(5-Methyl-1,2,4-Oxadiazol-3-Yl)Phenylboronic Acid
CAS No.	1217501-31-9
Molecular Formula	C9H9BN2O3
Molecular Weight	204.00 g/mol
Synonyms	[3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenyl]boronic acid; (3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenyl)boronic acid; 3-(5-Methyl-1,2,4-oxadiazol-3-yl)benzeneboronic acid; B-[3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenyl]boronic acid; 3-(5-Methyl-[1,2,4]oxadiazol-3-yl)-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-(5-Methyl-1,2,4-Oxadiazol-3-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high lot-to-lot consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects requiring adherence to cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.