Description

8-Fluoroquinoline-7-Boronic Acid is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated quinoline-based drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the fluorine atom and quinoline core enhance biological activity and stability.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other fluorinated functional polymers.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura palladium-catalyzed cross-coupling to introduce the 7-substituted quinoline moiety into more complex systems.
• Chemical Biology & Proteomics: Useful as a molecular tag or linker in the development of chemical probes and bioconjugates.
• Academic & R&D: A vital reagent for methodological development in organic synthesis and catalysis studies within university and corporate laboratories.

Basic Information

Product Name	8-Fluoroquinoline-7-Boronic Acid
CAS No.	1217500-71-4
Molecular Formula	C9H7BBrFNO2 (Pinacol ester form is common)
Molecular Weight	Contact for details
Synonyms	8-Fluoro-7-quinolineboronic Acid; (8-Fluoroquinolin-7-yl)boronic Acid; 7-Borono-8-fluoroquinoline; 8-Fluoroquinoline-7-boronic Acid Pinacol Ester; 8-Fluoro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; 8-Fluoro-7-quinolinylboronic Acid; CAS 1217500-71-4; Quinoline-7-boronic acid, 8-fluoro-
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-7-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for critical cross-coupling applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (argon/nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Typical grade, higher purity available)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.