Description

1-Boc-5-(Methoxycarbonyl)Indole-2-Boronic Acid is a high-value, multifunctional chemical building block designed for advanced organic synthesis. This compound matters for its role as a key intermediate in the construction of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel indole-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the introduction of the indole scaffold into complex molecular architectures.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the indole core's biological activity.
• Material Science: Potential precursor for the synthesis of organic electronic materials and functional polymers.
• Academic & Contract Research: Essential reagent for methodology development and library synthesis in academic and contract research organizations (CROs).
• Peptidomimetics: Employed in the design and synthesis of indole-containing peptidomimetics for probing biological pathways.

Basic Information

Product Name	1-Boc-5-(Methoxycarbonyl)Indole-2-Boronic Acid
CAS No.	1217500-60-1
Molecular Formula	C15H18BNO5
Molecular Weight	303.12 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-(methoxycarbonyl)-1H-indole-2-boronic acid; 5-Methoxycarbonyl-1-Boc-indole-2-boronic acid; 1-Boc-5-methoxycarbonylindole-2-boronic acid; 2-Borono-5-methoxycarbonyl-1-Boc-indole; tert-Butyl 5-(methoxycarbonyl)-2-borono-1H-indole-1-carboxylate; 1H-Indole-2-boronic acid, 1-[(1,1-dimethylethoxy)carbonyl]-5-(methoxycarbonyl)-; BOC-5-Methoxycarbonylindole-2-Boronic Acid
EINECS	Contact for details

Quality Control

Our 1-Boc-5-(Methoxycarbonyl)Indole-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.