Description

2-[(2,6-Dichlorophenyl)Amino]-N,n-Dimethylbenzeneacetamide-D4 is a deuterated analog of a key pharmaceutical intermediate, offering enhanced stability and utility in advanced research and development. This compound is critical for applications requiring precise isotopic labeling, such as in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, analytical reference standard producers, and manufacturers of active pharmaceutical ingredients (APIs) for the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled internal standard for precise quantitative analysis via LC-MS/MS and GC-MS in bioanalytical method development.
• Metabolite Identification & Tracing: Enables detailed study of drug metabolism pathways and the identification of metabolites in biological matrices.
• Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies: Used to improve the accuracy and reliability of data in drug absorption, distribution, metabolism, and excretion (ADME) studies.
• Reference Standard Production: Serves as a certified reference material (CRM) for quality control and regulatory compliance in API manufacturing.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high-precision calibration for analytical techniques requiring minimal measurement uncertainty.
• Drug Discovery & Medicinal Chemistry: Aids in the synthesis and evaluation of deuterated drug candidates, potentially offering improved metabolic profiles.

Basic Information

Product Name	2-[(2,6-Dichlorophenyl)Amino]-N,n-Dimethylbenzeneacetamide-D4
CAS No.	1217360-64-9
Molecular Formula	C16H12D4Cl2N2O
Molecular Weight	323.22 g/mol (deuterated form)
Synonyms	N,N-Dimethyl-2-[(2,6-dichlorophenyl)amino]benzeneacetamide-d4; Lidocaine-d4 impurity standard; Lignocaine-d4; Xylocaine-d4; α-Diethylamino-2,6-dimethylacetanilide-d4; Deuterated Lidocaine Related Compound; 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide-d4; [2,6-Dimethylphenyl)carbamoylmethyl]diethylammonium-d4
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment (D%), and chromatographic profile. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical reference standard and research markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D%)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.