Description

6-(n-Methylamidocarboxy)Pyridine-3-Boronic Acid is a high-purity, functionalized pyridine boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amide moiety for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with complex molecular architectures.
• Material Science: Employed in the creation of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl systems.
• Academic & Contract Research: Serves as a valuable reagent for methodology development and complex molecule synthesis in research laboratories.

Basic Information

Item	Detail
Product Name	6-(n-Methylamidocarboxy)Pyridine-3-Boronic Acid
CAS No.	1217340-94-7
Molecular Formula	C8H11BN2O3
Molecular Weight	194.00 g/mol
Synonyms	3-Pyridineboronic acid, 6-[(methylamino)carbonyl]-; 6-(Methylcarbamoyl)pyridine-3-boronic acid; 5-Borono-2-(N-methylcarbamoyl)pyridine; 2-(N-Methylcarbamoyl)-5-pyridineboronic acid; N-Methyl-5-boronopicolinamide; (6-(Methylcarbamoyl)pyridin-3-yl)boronic acid; 1217340-94-7; 5-Pyridineboronic acid, 2-[(methylamino)carbonyl]-
EINECS	Contact for details

Quality Control

Our 6-(n-Methylamidocarboxy)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.