Description

5-Hydroxy-1-[(E)-[5-(2,3,5,6-Tetradeuterio-4-Nitrophenyl)Furan-2-Yl]Methylideneamino]Imidazolidine-2,4-Dione is a deuterated derivative of a hydantoin-based compound, designed for advanced research and development applications. Its core value lies in its deuterium-labeled structure, which provides a stable isotopic marker for precise analytical studies in pharmacokinetics and metabolic research. This high-purity compound is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require isotopically labeled standards for mass spectrometry, tracer studies, and the development of novel therapeutic agents.

Application

• As a stable isotope-labeled internal standard for quantitative bioanalysis using LC-MS/MS.
• In pharmacokinetic (PK) and drug metabolism studies to track the fate of parent drug molecules.
• For use in deuterium exchange experiments and mechanistic studies in medicinal chemistry.
• As a key advanced intermediate in the synthesis of deuterated active pharmaceutical ingredients (APIs).
• In academic and industrial research focused on proteomics and metabolomics.
• For the development and validation of highly sensitive analytical methods in regulatory environments.

Basic Information

Product Name	5-Hydroxy-1-[(E)-[5-(2,3,5,6-Tetradeuterio-4-Nitrophenyl)Furan-2-Yl]Methylideneamino]Imidazolidine-2,4-Dione
CAS No.	1217225-15-4
Molecular Formula	C14H7D4N3O6
Molecular Weight	317.27 g/mol
Synonyms	5-Hydroxy-1-[(E)-[5-(2,3,5,6-Tetradeutero-4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione; Deuterated Nitrophenylfuran Hydantoin Derivative; [D4]-Labeled Hydantoin Intermediate; 1-[(E)-[5-(2,3,5,6-Tetradeuterio-4-Nitrophenyl)-2-Furanyl]Methyleneamino]-5-Hydroxy-2,4-Imidazolidinedione; Isotope-Labeled API Intermediate; CAS 1217225-15-4
EINECS	Contact for details

Quality Control

Every batch of our deuterated compounds is produced under strict quality control protocols to ensure isotopic purity and chemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (D%), chemical purity, and impurity profiles. Our quality systems are designed to support GMP and ISO standards for research and development materials, ensuring reliability for your most critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D%)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.