Description

1-(4-Chlorophenyl)Cyclobutane-D6 Carbonitrile is a deuterated isotopologue of a key pharmaceutical intermediate, where six hydrogen atoms are replaced with deuterium, offering enhanced metabolic stability for research and development. This compound is critical for creating deuterium-labeled drug candidates and internal standards for precise analytical quantification. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Deuterated Pharmaceutical Intermediate: Serves as a building block for synthesizing deuterium-labeled drug molecules with improved pharmacokinetic profiles.
• Mass Spectrometry Internal Standard: Used as a stable, isotopically labeled reference standard for accurate quantification in LC-MS and GC-MS analysis.
• Metabolic Studies: Enables detailed investigation of drug metabolism and pathways in preclinical research.
• Agrochemical Research: Acts as a precursor in the development of novel, labeled agrochemicals and their metabolites.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological mechanisms.
• Organic Synthesis Building Block: Utilized in advanced organic synthesis, particularly in cyclobutane and aryl nitrile chemistry.

Basic Information

Product Name	1-(4-Chlorophenyl)Cyclobutane-D6 Carbonitrile
CAS No.	1217114-23-2
Molecular Formula	C11H5D6ClN
Molecular Weight	~197.71 g/mol
Synonyms	1-(4-Chlorophenyl)cyclobutane-1-carbonitrile-d6; (4-Chlorophenyl)cyclobutanecarbonitrile-d6; 1-(p-Chlorophenyl)cyclobutanecarbonitrile-d6; 4-(1-Cyanocyclobutyl)chlorobenzene-d6; Cyclobutanecarbonitrile, 1-(4-chlorophenyl)-, d6-; 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile-d6; Deuterated 1-(4-Chlorophenyl)cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)Cyclobutane-D6 Carbonitrile is manufactured under strict quality systems to ensure high isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-enrichment), chemical purity by HPLC, and identity confirmation. We adhere to relevant standards for fine chemicals and deuterated compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.