Description

Glycinexylidide-D6 is a deuterium-labeled analog of the local anesthetic metabolite lidocaine. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic toxicology, and clinical diagnostics sectors who require precise quantification of lidocaine and its metabolites.

Application

• Internal Standard for LC-MS/MS: Primary application for the precise quantification of lidocaine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and bioavailability.
• Forensic Toxicology: Enables accurate measurement of lidocaine concentrations in post-mortem and anti-doping analyses.
• Clinical Diagnostics: Supports therapeutic drug monitoring (TDM) to optimize patient dosage and avoid toxicity.
• Metabolite Pathway Studies: Facilitates research into the metabolic fate of lidocaine and related compounds.
• Method Development & Validation: Serves as a critical reference material for developing and validating robust analytical methods in compliance with GLP/GMP guidelines.

Basic Information

Product Name	Glycinexylidide-D6
CAS No.	1217098-46-8
Molecular Formula	C10H9D6N2O
Molecular Weight	179.26 g/mol
Synonyms	2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide-d6; Lidocaine Metabolite (MEGX)-d6; Monoethylglycinexylidide-d6; N-(2,6-Dimethylphenyl)-2-(diethylamino)acetamide-d6; Glycinexylidide (Deuterated); MEGX-d6; GX-d6; Deutero-Glycinexylidide
EINECS	Contact for details

Quality Control

Every batch of Glycinexylidide-D6 is manufactured under strict quality systems and undergoes comprehensive analytical characterization. We guarantee high chemical and isotopic purity, supported by Certificates of Analysis (COA) that include data from NMR, HPLC, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for use as a certified reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.