Description

Diethyl[2-(4-Nitrophenoxy)Ethyl]Amine-D4 is a deuterium-labeled analog of a key chemical intermediate featuring a nitrophenoxyethylamine structure. This compound is specifically designed for use as an internal standard in mass spectrometry, enabling precise quantitative analysis and method development in research and quality control laboratories. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-fidelity isotopic standards for trace-level detection and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical deuterated internal standard for the accurate quantification of its non-labeled counterpart in bioanalytical methods, enhancing data reliability in pharmacokinetic and metabolism studies.
• Pharmaceutical Research & Development: Used in drug discovery and development for tracing and quantifying active pharmaceutical ingredients (APIs) and their metabolites during preclinical and clinical research phases.
• Analytical Method Development: Employed by analytical laboratories to validate and calibrate sensitive detection methods like High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS).
• Metabolite Identification: Aids in the structural elucidation and tracking of drug metabolites in complex biological matrices such as plasma, urine, and tissue samples.
• Agrochemical Analysis: Supports residue testing and environmental fate studies of related agrochemical compounds, ensuring compliance with regulatory safety standards.
• Chemical Synthesis Tracing: Functions as a labeled tracer in synthetic chemistry to study reaction mechanisms, pathways, and the stability of chemical intermediates.

Basic Information

Product Name	Diethyl[2-(4-Nitrophenoxy)Ethyl]Amine-D4
CAS No.	1216997-10-2
Molecular Formula	C₁₂H₁₄D₄N₂O₃
Molecular Weight	238.30 g/mol (deuterated form)
Synonyms	N,N-Diethyl-2-(4-nitrophenoxy)ethan-1-amine-d4; 2-(4-Nitrophenoxy)-N,N-diethylethanamine-d4; 4-Nitrophenoxyethyl-diethyl-amine-d4; Diethyl(2-(4-nitrophenoxy)ethyl)amine-1,1,2,2-d4; Deuterated Diethyl(2-(4-nitrophenoxy)ethyl)amine; D4-Labeled DEANP; DEANP-d4; (2-(4-Nitrophenoxy)ethyl)diethylamine-d4
EINECS	Contact for details

Quality Control

Every batch of Diethyl[2-(4-Nitrophenoxy)Ethyl]Amine-D4 is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with specifications typically meeting or exceeding 98.0% chemical purity (by HPLC) and 98.0 atom % D isotopic purity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and isotopic composition are provided to ensure traceability and support your regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown solid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (atom % D)	≥ 98.0%
Chemical Purity (by NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.