Description

2-Pyridylacetic Acid-D6 Hydrochloride is a high-purity, isotopically labeled derivative of 2-pyridylacetic acid, where six hydrogen atoms are replaced by deuterium. This deuteration is critical for enhancing analytical precision and reducing background interference in sensitive detection methods. It serves as a vital internal standard and reference material for researchers and quality control laboratories in the pharmaceutical and agrochemical sectors, ensuring accurate quantification and metabolic pathway tracing.

Application

• Primary use as a deuterated internal standard for the accurate quantification of 2-pyridylacetic acid and related metabolites in bioanalytical studies using LC-MS/MS and GC-MS.
• Critical reference material in pharmaceutical research and development, particularly for pharmacokinetic (PK) and pharmacodynamic (PD) studies of drug candidates containing the pyridyl moiety.
• Essential tool in metabolomics and proteomics research for tracing biochemical pathways and studying drug metabolism.
• Used in the development and validation of analytical methods to meet regulatory compliance standards (e.g., FDA, EMA) for drug approval.
• Application in agrochemical research for the analysis of pesticide metabolites and environmental fate studies.
• Utilized in academic and institutional research involving mechanistic organic chemistry and synthesis of labeled compounds.

Basic Information

Product Name	2-Pyridylacetic Acid-D6 Hydrochloride
CAS No.	1216972-24-5
Molecular Formula	C7H2D6ClNO2 • HCl
Molecular Weight	Contact for details
Synonyms	2-(Pyridin-2-yl)acetic-2,2,3,3,4,5-d6 Acid Hydrochloride; (Pyridin-2-yl-d5)acetic-2,2-d2 Acid Hydrochloride; α-Pyridylacetic Acid-D6 HCl; 2-Pyridyl-D5-acetic-2,2-d2 Acid Hydrochloride; Deuterated 2-Pyridylacetic Acid Hydrochloride; 2-Pyridineacetic-d6 Acid Hydrochloride; 2-Picolyl-d6 Acid Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridylacetic Acid-D6 Hydrochloride is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic techniques, to ensure compliance with industry standards for isotopic purity and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.