Description

(+/-)-4-Chlorophenyl-5-[(3,4-Isopropylidine)-2-Methylpyridine]Methanol-D4 is a deuterated derivative of a complex pyridine-based chiral alcohol, serving as a critical isotopically labeled intermediate in advanced chemical synthesis. Its core value lies in providing a stable, non-radioactive isotopic label for mechanistic studies, metabolic pathway tracing, and the development of high-performance analytical standards. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors, particularly for those developing novel active ingredients or requiring precise internal standards for mass spectrometry.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled building block for synthesizing isotopically labeled drug candidates for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Metabolic Pathway Analysis: Used as a tracer to elucidate metabolic pathways and identify metabolites in biological systems without interfering with the compound's biological activity.
• Internal Standard for LC-MS/MS: Provides a highly reliable and chemically identical internal standard for the quantitative bioanalysis of its non-deuterated counterpart, improving assay accuracy and precision.
• Agrochemical Development: Employed in the synthesis of labeled pesticides or herbicides to study environmental fate, degradation pathways, and residue analysis.
• Chemical Mechanism Probes: Utilized in mechanistic organic chemistry to investigate reaction pathways, isotope effects, and catalytic cycles.
• Reference Material Production: Serves as a certified reference material (CRM) or high-purity standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	(+/-)-4-Chlorophenyl-5-[(3,4-Isopropylidine)-2-Methylpyridine]Methanol-D4
CAS No.	1216968-24-9
Molecular Formula	C₁₆H₁₃D₄ClNO₂ *
Molecular Weight	~293.80 g/mol *
Synonyms	4-Chlorophenyl-5-(3,4-isopropylidenedioxy-2-methylpyridin-5-yl)methanol-d4
(±)-5-[(3,4-Isopropylidenedioxy-2-methylpyridin-5-yl)]-(4-chlorophenyl)methanol-d4
Deuterated 4-Chlorophenyl Pyridine Methanol Derivative
4-Chloro-α-[(3,4-Isopropylidenedioxy-2-methyl-5-pyridinyl)]benzenemethanol-d4
D4-Labeled Pyridine Methanol Intermediate
CAS 1216968-24-9
Contact for additional synonyms
EINECS	Contact for details

* Calculated based on the most probable structure. Contact us for confirmed analytical data.

Quality Control

Our deuterated chemicals are produced under strict quality management to ensure isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR (¹H, ¹³C, ²H), High-Resolution Mass Spectrometry (HRMS), and HPLC to confirm structure, isotopic enrichment (D-content), and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (²H NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.