Description

Carbinoxamine-D6 Maleate Salt is a deuterium-labeled internal standard of the antihistamine carbinoxamine, essential for precise quantitative analysis. This high-purity, isotopically enriched compound is critical for ensuring accuracy and reliability in mass spectrometry-based methods. It is primarily utilized by pharmaceutical research laboratories, contract research organizations (CROs), and analytical testing facilities for pharmacokinetic studies, drug metabolism research, and bioanalytical method development and validation.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference in liquid chromatography-tandem mass spectrometry for bioanalysis.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking and measurement of the parent drug carbinoxamine in biological matrices like plasma, serum, and urine.
• Bioanalytical Method Development: Used to validate and optimize analytical assays for drug concentration determination, ensuring method robustness and regulatory compliance.
• Drug Impurity Profiling: Aids in the identification and quantification of related substances and degradation products in pharmaceutical formulations.
• Clinical Research: Supports clinical trial studies requiring high-precision measurement of drug levels in patient samples.
• Forensic Toxicology: Employed in confirmatory testing for the presence and concentration of antihistamines in forensic samples.

Basic Information

Item	Detail
Product Name	Carbinoxamine-D6 Maleate Salt
CAS No.	1216872-59-1
Molecular Formula	C20H19D6ClN2O4
Molecular Weight	Approx. 406.90 g/mol
Synonyms	Carbinoxamine-d6; 2-[(4-Chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine-d6 Maleate; Carbinoxamine (phenyl-d5, N,N-dimethyl-d) Maleate; Deutero-labeled Carbinoxamine Maleate; Carbinoxamine Internal Standard; [phenyl-d5]-Carbinoxamine Maleate
EINECS	Contact for details

Quality Control

Every batch of Carbinoxamine-D6 Maleate Salt is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity required for analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for isotopic purity, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (Chemical Purity)
Isotopic Purity (MS)	≥98.0 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.