Description

4-(Chloromethyl)-2-[Isopropyl-1,1,1,3,3,3-D6]-4-Thiazolyl Hydrochloride Salt is a high-purity, deuterated building block of significant value in advanced chemical synthesis. Its core value proposition lies in its role as a stable isotope-labeled intermediate, enabling precise metabolic and pharmacokinetic studies in pharmaceutical research. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require isotopically labeled compounds for drug discovery, development, and regulatory submission.

Application

• Deuterated Pharmaceutical Intermediate: A critical precursor in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) for improved metabolic stability and pharmacokinetic profiling.
• Metabolic Pathway Tracer: Used in mass spectrometry-based studies to track drug metabolism and distribution within biological systems.
• Internal Standard for Bioanalysis: Serves as a high-quality internal standard in LC-MS/MS methods for the accurate quantification of drugs and metabolites in biological matrices.
• Agrochemical Research: Employed in the development of novel, isotopically labeled agrochemicals for environmental fate and residue analysis studies.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for investigating biological mechanisms and protein interactions.
• Process Chemistry & Scale-up: Supports process development and optimization for the commercial production of deuterated compounds.

Basic Information

Product Name	4-(Chloromethyl)-2-[Isopropyl-1,1,1,3,3,3-D6]-4-Thiazolyl Hydrochloride Salt
CAS No.	1216869-95-2
Molecular Formula	C8H7D6Cl2NOS
Molecular Weight	254.20 g/mol
Synonyms	2-(Isopropyl-d6)-4-(chloromethyl)thiazole Hydrochloride; 4-(Chloromethyl)-2-(propan-2-yl-1,1,1,3,3,3-d6)-1,3-thiazole Hydrochloride; 4-(Chloromethyl)-2-(isopropyl-d6)thiazole HCl; Deuterated 4-(Chloromethyl)-2-isopropylthiazole Hydrochloride; (Isopropyl-d6)-4-chloromethylthiazole Hydrochloride; 4-Chloromethyl-2-(isopropyl-d6)thiazole Hydrochloride; 1216869-95-2
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-[Isopropyl-1,1,1,3,3,3-D6]-4-Thiazolyl Hydrochloride Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity, isotopic enrichment (D6), and impurity profiles. We support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.