Description

(3-Methyl-D3-Amino)Propionitrile is a deuterium-labeled organic compound, specifically a nitrile derivative with a trideuterated methylamino group. This stable isotope-labeled analog is critical for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a metabolic tracer, or a synthetic building block in deuterium-labeling studies.

Application

• Pharmaceutical Research & Development: Serves as a key deuterated intermediate in the synthesis of isotopically labeled drug candidates for pharmacokinetic (PK), pharmacodynamic (PD), and metabolism (ADME) studies.
• Analytical Chemistry Standards: Used as a high-purity internal standard in quantitative mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS) methods to ensure accurate measurement of target analytes.
• Metabolic Pathway Tracing: Employed in biomedical and biochemical research to trace and elucidate metabolic pathways and mechanisms of action due to its stable deuterium labels.
• Agrochemical Development: Acts as a building block for creating deuterium-labeled pesticides or herbicides to study their environmental fate, degradation, and residue analysis.
• Material Science Research: Can be utilized in the development of novel organic materials where deuterium incorporation is used to modify physical properties or study molecular dynamics.
• NMR Spectroscopy: Useful as a probe or reference compound in Nuclear Magnetic Resonance (NMR) spectroscopy due to the distinct signal of deuterium.

Basic Information

Product Name	(3-Methyl-D3-Amino)Propionitrile
CAS No.	1216852-82-2
Molecular Formula	C4H5D3N2
Molecular Weight	87.13 g/mol
Synonyms	3-[(Methyl-d3)amino]propanenitrile; (Methyl-d3)aminopropionitrile; 3-(Methyl-d3-amino)propionitrile; CD3NHCH2CH2CN; N-(Methyl-d3)-3-aminopropionitrile; β-[(Methyl-d3)amino]propionitrile; 3-(N-Methyl-d3-amino)propionitrile; Propanenitrile, 3-[(methyl-d3)amino]-
EINECS	Contact for details

Quality Control

Our deuterated chemicals, including (3-Methyl-D3-Amino)Propionitrile, are produced and tested under strict quality management systems. Each batch is characterized by advanced analytical techniques such as NMR, MS, and HPLC to confirm isotopic purity, chemical purity, and identity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical assay, and impurity profile is provided with every shipment to ensure reliable and reproducible results for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage under optimal conditions, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0% (by MS or NMR)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.