Description

2-Amino-3,4,7,8-Tetramethyl-3H-Imidazo[4,5-F]Quinoxaline-D3 is a stable isotope-labeled analog of a heterocyclic aromatic amine, specifically deuterated at three positions. This compound is of significant value as a high-purity internal standard for precise quantitative analysis in advanced mass spectrometry. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, food safety, and environmental toxicology sectors for method development and accurate quantification of its non-deuterated counterpart.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of 2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-f]quinoxaline (DiMeIQx) in complex matrices, correcting for analyte loss during sample preparation and instrument variability.
• Food Safety & Contaminant Analysis: Used in the detection and measurement of heterocyclic aromatic amines (HAAs), which are potential carcinogens formed in cooked meats, ensuring compliance with food safety monitoring programs.
• Metabolic and Pharmacokinetic Studies: Employed in in vitro and in vivo research to track the absorption, distribution, metabolism, and excretion (ADME) profiles of HAAs.
• Environmental and Occupational Exposure Assessment: Facilitates biomonitoring studies to assess human exposure to dietary and environmental pollutants.
• Certified Reference Material (CRM) Production: Serves as a key component in the formulation of certified standards for quality control and laboratory accreditation.
• Toxicological Research: Enables precise dosing and tracking in studies investigating the genotoxicity and carcinogenicity of cooked food mutagens.

Basic Information

Product Name	2-Amino-3,4,7,8-Tetramethyl-3H-Imidazo[4,5-F]Quinoxaline-D3
CAS No.	1216791-04-6
Molecular Formula	C13H12D3N5
Molecular Weight	234.31 g/mol
Synonyms	DiMeIQx-d3; 2-Amino-3,4,7,8-tetramethylimidazo[4,5-f]quinoxaline-d3; 3,4,7,8-Tetramethyl-3H-imidazo[4,5-f]quinoxalin-2-amine-d3; Deuterated DiMeIQx; [2H3]-DiMeIQx; 2-Aminodimethylimidazoquinoxaline-d3; Internal Standard for DiMeIQx
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,4,7,8-Tetramethyl-3H-Imidazo[4,5-F]Quinoxaline-D3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical reference standard applications. Comprehensive Certificates of Analysis (COA) are provided, detailing results from NMR (Nuclear Magnetic Resonance), HPLC (High-Performance Liquid Chromatography), and MS (Mass Spectrometry) to confirm identity, chemical purity, isotopic enrichment, and absence of the non-deuterated compound.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (NMR)	Conforms to structure
Identification (HPLC-MS)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Chemical Purity (vs. Non-deuterated)	≤ 0.5%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.