Description

Tinidazole-D5 CAS NO 1216767-04-2 is a deuterium-labeled analog of the nitroimidazole antibiotic Tinidazole, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of mass spectrometry-based analyses, particularly in pharmacokinetic and metabolism studies. It is a critical tool for pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities that require precise quantification of Tinidazole in complex biological matrices.

Application

• Primary use as an Internal Standard for the quantification of Tinidazole via LC-MS/MS and GC-MS in bioanalytical studies.
• Supporting Pharmacokinetic (PK) and Bioequivalence Studies to track drug absorption, distribution, metabolism, and excretion.
• Metabolite identification and profiling in Drug Metabolism and Pharmacokinetics (DMPK) research.
• Ensuring data integrity and method validation for Regulatory Submissions to agencies like the FDA and EMA.
• Quality control and impurity profiling in Active Pharmaceutical Ingredient (API) manufacturing.
• Use in Clinical Research for accurate therapeutic drug monitoring.

Basic Information

Product Name	Tinidazole-D5
CAS No.	1216767-04-2
Molecular Formula	C8H6D5N3O4S
Molecular Weight	248.29 g/mol
Synonyms	1-[2-(Ethylsulfonyl-d5)ethyl]-2-methyl-5-nitroimidazole; Tinidazole-d5; Deuterated Tinidazole; Tinidazole (ethyl-d5); Tinidazole Internal Standard; [2H5]-Tinidazole; 2-Methyl-1-[2-[(2H5)ethylsulfonyl]ethyl]-5-nitro-1H-imidazole
EINECS	Contact for details

Quality Control

Our Tinidazole-D5 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and purity by HPLC. We ensure compliance with relevant standards for stable isotope-labeled compounds used in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.