Description

2-Chloro-1,3-Propanediol-D5 (Major) is a deuterium-labeled isotopologue of 2-chloro-1,3-propanediol, a compound of significant interest in analytical chemistry and life sciences research. This stable isotope-labeled standard is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily utilized by researchers and quality control laboratories in the food safety, environmental monitoring, and pharmaceutical sectors who require precise internal standards for the detection and quantification of chloropropanols, such as 3-MCPD, in complex matrices.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference for GC-MS or LC-MS/MS analysis of chloropropanols and related contaminants.
• Food Safety Testing: Used in the accurate quantification of 3-MCPD and other process contaminants in edible oils, soy sauces, and hydrolyzed vegetable proteins.
• Metabolic and Pharmacokinetic Studies: Enables the tracing and quantification of chloropropanediol metabolites in biological systems for toxicological research.
• Method Development and Validation: Essential for developing, calibrating, and validating analytical methods to meet stringent regulatory guidelines.
• Quality Control & Reference Material: Acts as a high-purity certified reference material (CRM) for laboratory proficiency testing and quality assurance programs.
• Environmental Analysis: Applied in monitoring trace levels of chloropropanols in water and environmental samples.

Basic Information

Product Name	2-Chloro-1,3-Propanediol-D5 (Major)
CAS No.	1216764-05-4
Molecular Formula	C₃H₂D₅ClO₂
Molecular Weight	~129.56 g/mol
Synonyms	3-MCPD-d5; 3-Chloro-1,2-propanediol-d5; 2-Chloropropane-1,3-diol-d5; α-Chlorohydrin-d5; Glycerol 1-chloro-2,3-dihydroxy-d5; 1-Chloro-2,3-dihydroxypropane-d5; Deuterated 3-MCPD; [²H₅]-3-MCPD
EINECS	Contact for details

Quality Control

Our 2-Chloro-1,3-Propanediol-D5 (Major) is manufactured under controlled conditions to ensure exceptional isotopic purity and chemical stability. Each batch undergoes rigorous analysis using advanced techniques including NMR and mass spectrometry to confirm deuterium incorporation and chemical purity. Certificates of Analysis (COA) detailing batch-specific results for isotopic purity, chemical purity, and solvent content are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.