Description

n-(1,1,2,2,2-Pentadeuterioethyl)-1,3-Benzodioxol-5-Amine is a deuterated derivative of a benzodioxolylamine, a compound of significant interest in advanced research and development. This product matters for its role as a stable isotope-labeled internal standard, which is critical for ensuring accuracy and reliability in quantitative analytical methods. It is primarily needed by pharmaceutical, agrochemical, and academic research laboratories engaged in drug metabolism studies (DMPK), bioanalytical method development, and environmental fate analysis.

Application

• As a stable isotope-labeled internal standard for the precise quantification of its non-deuterated counterpart in complex biological matrices using LC-MS/MS.
• In pharmacokinetic and drug metabolism studies (DMPK) to track the absorption, distribution, metabolism, and excretion of active pharmaceutical ingredients.
• For bioanalytical method development and validation in clinical and preclinical research to meet regulatory requirements for selectivity and accuracy.
• In environmental analysis to study the degradation pathways and persistence of similar chemical structures.
• As a key synthetic intermediate in the preparation of more complex deuterated molecules for research purposes.
• For use in NMR spectroscopy as a tool to elucidate reaction mechanisms or molecular structures without signal interference from protons.

Basic Information

Product Name	n-(1,1,2,2,2-Pentadeuterioethyl)-1,3-Benzodioxol-5-Amine
CAS No.	1216722-76-7
Molecular Formula	C9H6D5NO2
Molecular Weight	~183.21 g/mol
Synonyms	5-[(1,1,2,2,2-Pentadeuterioethyl)amino]-1,3-benzodioxole; 1,3-Benzodioxol-5-amine, N-(1,1,2,2,2-pentadeuterioethyl)-; Deuterated 3,4-Methylenedioxy-N-ethylamphetamine (d5-MDEA) precursor; N-Ethyl-d5-1,3-benzodioxol-5-amine; 3,4-(Methylenedioxy)-N-ethyl-d5-amphetamine amine; N-(Pentadeuterioethyl)piperonylamine; 5-(Aminoethyl-d5)-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high chemical and isotopic purity, which is paramount for their use as analytical standards. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment (D-content), and impurity profile is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.