Description

2-Benzylamino-2-Methyl-1-Propanol-D6 is a deuterated analog of 2-Benzylamino-2-methyl-1-propanol, where six hydrogen atoms are replaced with deuterium, a stable hydrogen isotope. This deuteration is critical for applications requiring enhanced analytical precision, such as internal standards for mass spectrometry, which significantly improves the accuracy and reliability of quantitative analysis. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies engaged in advanced analytical chemistry, drug metabolism and pharmacokinetics (DMPK) studies, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical, non-interfering reference compound for the precise quantification of its non-deuterated counterpart in complex biological matrices like plasma, serum, and tissue homogenates.
• Drug Metabolism and Pharmacokinetics (DMPK) Research: Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of pharmaceutical compounds.
• Analytical Method Development and Validation: Essential for developing and validating highly sensitive and specific LC-MS/MS methods in bioanalytical laboratories.
• Deuterated Pharmaceutical Intermediate: Acts as a key building block in the synthesis of more complex deuterated molecules for pharmaceutical research, where deuteration can alter metabolic pathways.
• NMR Spectroscopy Studies: Useful as a probe in nuclear magnetic resonance (NMR) spectroscopy due to the distinct magnetic properties of deuterium, aiding in structural elucidation and reaction monitoring.
• Chemical Reference Material: Provides a certified, high-purity standard for quality control and calibration in analytical testing.

Basic Information

Product Name	2-Benzylamino-2-Methyl-1-Propanol-D6
CAS No.	1216719-27-5
Molecular Formula	C11H11D6NO
Molecular Weight	~185.29 g/mol
Synonyms	2-(Benzylamino)-2-methyl-1-propanol-d6; 2-Methyl-2-(phenylmethylamino)-1-propanol-d6; 1-Propanol, 2-(benzylamino)-2-methyl-d6; Deutrated AMPB; d6-2-Benzylamino-2-methylpropan-1-ol; BAMP-d6; (2-Hydroxy-1,1-dimethylethyl)(phenylmethyl)amine-d6
EINECS	Contact for details

Quality Control

Every batch of 2-Benzylamino-2-Methyl-1-Propanol-D6 is manufactured and analyzed under strict quality management protocols to ensure exceptional purity and isotopic enrichment, which are paramount for its use as an analytical standard. Our quality assurance includes comprehensive testing via NMR, HPLC, and mass spectrometry to confirm chemical identity, purity, and deuterium incorporation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We adhere to cGMP principles where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.