Description

Ethyl 3-Amino-6-Bromobenzothiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a functionalized benzothiophene core. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules, particularly in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents or functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile amino and bromo functional groups.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents and pesticides with novel modes of action.
• Material Science: Employed in the research and development of organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions for clinical trial materials.

Basic Information

Product Name	Ethyl 3-Amino-6-Bromobenzothiophene-2-Carboxylate
CAS No.	1216708-87-0
Molecular Formula	C11H10BrNO2S
Molecular Weight	300.17 g/mol
Synonyms	Ethyl 3-Amino-6-Bromobenzo[b]thiophene-2-Carboxylate; 6-Bromo-3-Aminobenzo[b]thiophene-2-Carboxylic Acid Ethyl Ester; 3-Amino-6-Bromobenzothiophene-2-Carboxylic Acid Ethyl Ester; 2-Carbethoxy-3-Amino-6-Bromobenzothiophene; Ethyl 3-Amino-6-Bromo-1-Benzothiophene-2-Carboxylate; 1216708-87-0; BAEC; 6-Bromo-3-aminobenzo[b]thiophene-2-ethyl carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-6-Bromobenzothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.