Description

Ethyl 3-Amino-4-Iodo-1-Benzothiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its unique molecular architecture, which combines an amino group, an iodine substituent, and a carboxylate ester on a benzothiophene core, enabling diverse derivatization pathways. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its electron-rich and modifiable structure.
• Chemical Synthesis: The iodine atom provides a versatile handle for cross-coupling reactions (e.g., Suzuki, Sonogashira), while the amino and ester groups allow for further functionalization.
• Dye & Pigment Industry: Utilized in the synthesis of specialized dyes and organic pigments where the benzothiophene unit contributes to color and stability properties.

Basic Information

Item	Detail
Product Name	Ethyl 3-Amino-4-Iodo-1-Benzothiophene-2-Carboxylate
CAS No.	1216596-20-1
Molecular Formula	C11H10INO2S
Molecular Weight	347.17 g/mol
Synonyms	3-Amino-4-iodo-1-benzothiophene-2-carboxylic acid ethyl ester; Ethyl 3-amino-4-iodobenzo[b]thiophene-2-carboxylate; 4-Iodo-3-aminobenzo[b]thiophene-2-carboxylic acid ethyl ester; 1-Benzothiophene-2-carboxylic acid, 3-amino-4-iodo-, ethyl ester; AI3-53162; BBL011359; STK562159; ZINC000003869756
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-4-Iodo-1-Benzothiophene-2-Carboxylate is produced and tested under a strict quality management system to ensure consistency and reliability for your research and production needs. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Light yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.