Description

n-(4-Methyl-D3-Benzoyl-D4)Glycine is a high-purity, deuterium-labeled chemical reference standard. This compound is specifically designed for use in quantitative analytical methods, providing enhanced sensitivity and accuracy in mass spectrometry-based detection. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced material sectors who require precise internal standards for method development and validation.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable isotope-labeled internal standard in bioanalytical method development for pharmacokinetic and metabolomic studies.
• Pharmaceutical Impurity Profiling: Used as a reference marker in the identification and quantification of process-related impurities and degradation products in Active Pharmaceutical Ingredients (APIs).
• Metabolic Pathway Tracing: Enables detailed investigation of drug metabolism and biochemical pathways in preclinical research.
• Environmental Analysis: Serves as a recovery standard in the analysis of complex environmental samples for trace chemical contaminants.
• Certified Reference Material (CRM): Suitable for use in the preparation of certified reference materials to ensure measurement traceability and laboratory accreditation (ISO/IEC 17025).
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Useful as a deuterated analog in NMR studies to simplify spectral analysis.

Basic Information

Product Name	n-(4-Methyl-D3-Benzoyl-D4)Glycine
CAS No.	1216588-60-1
Molecular Formula	C10H4D7NO3
Molecular Weight	~197.24 g/mol
Synonyms	N-(4-(Trideuteriomethyl)benzoyl-d4)glycine; Glycine, N-[4-(methyl-d3)benzoyl-d4]-; Deuterated N-(4-Methylbenzoyl)glycine; d7-N-(4-Methylbenzoyl)glycine; Isotope-labeled Hippuric Acid Derivative; 4-Methyl-D3-benzoyl-D4-glycine; (4-Methyl-d3-benzoyl-d4)aminoacetic Acid
EINECS	Contact for details

Quality Control

Every batch of n-(4-Methyl-D3-Benzoyl-D4)Glycine is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and all relevant specifications is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.