Description

Methanesulfonyl Chloride-D3,13C is a stable isotope-labeled derivative of methanesulfonyl chloride, a versatile sulfonylating reagent. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry, providing unmatched accuracy and reliability in analytical measurements. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced material sectors who require precise quantification of methanesulfonyl chloride or its metabolites in complex matrices.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in pharmacokinetic and metabolism studies.
• Quantitative analysis of methanesulfonyl chloride residues in pharmaceutical intermediates and active ingredients.
• Tracer studies in chemical reaction mechanisms and pathway elucidation within organic synthesis.
• High-purity reference material for calibrating analytical instrumentation in regulatory and quality control environments.
• Use in the synthesis of deuterium and carbon-13 labeled target molecules for advanced research applications.
• Critical component in method development and validation for compliance with FDA, EMA, and ICH guidelines.

Basic Information

Item	Detail
Product Name	Methanesulfonyl Chloride-D3,13C
CAS No.	1216581-01-9
Molecular Formula	CD313ClO2S
Molecular Weight	118.56 g/mol (approx.)
Synonyms	Deuterated Methanesulfonyl Chloride; [D3,13C]-Methanesulfonyl Chloride; Mesyl Chloride-D3,13C; Methanesulfonyl-13C chloride (trideuteriomethyl); Isotopically Labeled Methanesulfonyl Chloride; MSC-d3-13C; 13C Labeled Methanesulfonyl Chloride-D3
EINECS	Contact for details

Quality Control

Our Methanesulfonyl Chloride-D3,13C is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, MS, and HPLC, to confirm isotopic enrichment and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity	≥ 99 atom % 13C; ≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.