Description

n-(3-Methyl-D3-Benzoyl-D4)Glycine is a stable isotope-labeled derivative of a key hippuric acid analog, specifically designed for advanced analytical applications. This high-purity compound is essential for researchers and manufacturers requiring precise internal standards for mass spectrometry, ensuring accurate quantification and reliable data integrity. It is primarily utilized in pharmaceutical research, clinical diagnostics, and environmental analysis where deuterium labeling is critical for method validation and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in bioanalytical methods for drug metabolism and pharmacokinetic (DMPK) studies.
• Pharmaceutical Impurity Profiling: Used in the development and validation of analytical methods to identify and quantify related substances and degradation products.
• Clinical Diagnostic Assays: Enables precise measurement of specific biomarkers or metabolites in complex biological matrices like serum or urine.
• Metabolomics Research: Facilitates accurate tracking and quantification of metabolic pathways in both in vitro and in vivo systems.
• Environmental Analysis: Applied as a labeled surrogate in the detection and analysis of chemical residues in environmental samples.
• Quality Control & Method Development: Provides a reliable benchmark for ensuring the accuracy, precision, and robustness of analytical procedures in QA/QC laboratories.

Basic Information

Product Name	n-(3-Methyl-D3-Benzoyl-D4)Glycine
CAS No.	1216551-07-3
Molecular Formula	C10H6D7NO3
Molecular Weight	~197.24 g/mol
Synonyms	N-(3-(Trideuteriomethyl)-d4-benzoyl)glycine; Deuterated Hippuric Acid Derivative; 3-Methyl-d3-benzoyl-d4-glycine; Glycine, N-[3-(methyl-d3)-d4-benzoyl]-; Hippuric Acid-d7 (3-methyl derivative); Stable Isotope Labeled Glycine Conjugate; D7-Labeled Benzoylglycine Analog
EINECS	Contact for details

Quality Control

Every batch of n-(3-Methyl-D3-Benzoyl-D4)Glycine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity, verified by advanced techniques including NMR, HPLC, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.