Description

Rac-n-Benzyl-n-[2-Hydroxyl-2-(4-Benzyloxy-3-Formamidophenyl)-Ethyl]-3-(4-Methoxyphenyl)-2-Propylamine-D6 is a deuterated isotopologue of a complex amine derivative, designed for advanced research and development applications. This compound matters as a high-purity, stable isotope-labeled standard, enabling precise analytical quantification and metabolic pathway tracing in sophisticated studies. It is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and analytical laboratories working on method development, pharmacokinetics, and bioanalytical assays.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the accurate quantification of its non-deuterated counterpart in complex biological matrices like plasma, serum, and tissue homogenates.
• Metabolic Studies & Drug Disposition: Used in pharmaceutical research to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of lead compounds and active pharmaceutical ingredients (APIs).
• Bioanalytical Method Development & Validation: Essential for developing and validating robust, sensitive, and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Pharmacokinetic (PK) and Pharmacodynamic (PD) Research: Enables precise tracking of drug concentration over time to establish dosing regimens and efficacy.
• Stable Isotope Labeling in Chemical Synthesis: Acts as a building block or tracer in synthetic chemistry to study reaction mechanisms or create labeled derivatives.
• Quality Control & Impurity Profiling: Supports impurity identification and quantification in API batches, ensuring product safety and consistency.

Basic Information

Product Name	Rac-n-Benzyl-n-[2-Hydroxyl-2-(4-Benzyloxy-3-Formamidophenyl)-Ethyl]-3-(4-Methoxyphenyl)-2-Propylamine-D6
CAS No.	1216518-77-2
Molecular Formula	C32H31D6N2O3 (Contact for exact formula confirmation)
Molecular Weight	~509.7 g/mol (Contact for exact weight)
Synonyms	Benzyl-[2-hydroxy-2-(4-benzyloxy-3-formamidophenyl)ethyl]-[3-(4-methoxyphenyl)propyl]amine-d6; Deuterated Rac-N-Benzyl-N-[2-Hydroxy-2-(4-Benzyloxy-3-Formamidophenyl)Ethyl]-3-(4-Methoxyphenyl)-2-Propylamine; 3-(4-Methoxyphenyl)-2-propylamine-D6 derivative; (RS)-N-Benzyl-N-[2-hydroxy-2-(4-benzyloxy-3-formamidophenyl)ethyl]-3-(4-methoxyphenyl)propan-1-amine-d6; Isotopically Labeled Amine Standard; CAS 1216518-77-2
EINECS	Contact for details

Quality Control

Our deuterated standards are produced and controlled under a strict quality management system. Each batch of Rac-n-Benzyl-n-[2-Hydroxyl-2-(4-Benzyloxy-3-Formamidophenyl)-Ethyl]-3-(4-Methoxyphenyl)-2-Propylamine-D6 undergoes rigorous analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity, chemical purity, and identity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, supporting traceability and compliance for your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.