Description

2-n-Butyl-4-[(2-Bromoethoxy-D4)-3,5-Diiodobenzoyl]Benzofuran CAS NO 1216376-62-3 is a high-purity, deuterated benzofuran derivative, a critical building block in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate for synthesizing novel therapeutic agents, particularly in metabolic and cardiovascular disease research where isotopic labeling is essential for pharmacokinetic and metabolic studies. This compound is specifically engineered for use by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug discovery programs requiring labeled compounds for tracer studies and analytical method development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of deuterated active pharmaceutical ingredients (APIs) for clinical research.
• Metabolic Tracer: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion (ADME) of lead compounds.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for method validation and quantification in bioanalytical assays (LC-MS/MS).
• Isotope Labeling Research: Enables the study of reaction mechanisms and metabolic pathways in medicinal chemistry due to its deuterium-labeled ethoxy moiety.
• Preclinical Development: Utilized in the development of novel benzofuran-based therapeutics targeting specific enzyme pathways.

Basic Information

Item	Details
Product Name	2-n-Butyl-4-[(2-Bromoethoxy-D4)-3,5-Diiodobenzoyl]Benzofuran
CAS No.	1216376-62-3
Molecular Formula	C21H17D4BrI2O3
Molecular Weight	Contact for details
Synonyms	2-Butyl-4-[(2-bromoethoxy-1,1,2,2-d4)-3,5-diiodobenzoyl]benzofuran; 4-(2-Bromoethoxy-d4)-3,5-diiodobenzoyl-2-butylbenzofuran; Deuterated Benzofuran Bromoethoxy Diiodo Derivative; 1216376-62-3; 2-n-Butyl-4-(3,5-diiodo-2-(2-bromoethoxy-d4)benzoyl)benzofuran; BDB-d4 Intermediate; [D4]-2-Bromoethyl Ether Benzofuran Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-n-Butyl-4-[(2-Bromoethoxy-D4)-3,5-Diiodobenzoyl]Benzofuran is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.