Description

(4-Bromophenyl)(Cyclobutyl)Methanol CAS NO 1216219-03-2 is a versatile chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromophenyl group and a cyclobutyl moiety, makes it a valuable precursor for constructing complex molecules with specific stereochemistry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Ligand and Catalyst Precursor: Used in the synthesis of specialized phosphine or nitrogen-based ligands for asymmetric catalysis and cross-coupling reactions.
• Agrochemical Research: Acts as a building block for novel herbicides, fungicides, and plant growth regulators requiring specific three-dimensional architecture.
• Material Science Monomer: Potential precursor for specialty polymers and liquid crystals, leveraging the rigidity of the cyclobutane ring and reactivity of the bromine atom.
• Chemical Biology Probe Development: Utilized in creating molecular probes and tool compounds for studying biological pathways and protein interactions.

Basic Information

Product Name	(4-Bromophenyl)(Cyclobutyl)Methanol
CAS No.	1216219-03-2
Molecular Formula	C11H13BrO
Molecular Weight	241.13 g/mol
Synonyms	Cyclobutyl(4-bromophenyl)methanol; (4-Bromophenyl)-cyclobutylmethanol; 1-(4-Bromophenyl)-1-cyclobutylmethanol; α-Cyclobutyl-4-bromobenzyl Alcohol; 4-Bromo-α-cyclobutylbenzenemethanol; (4-Bromophenyl)(cyclobutyl)carbinol
EINECS	Contact for details

Quality Control

Our (4-Bromophenyl)(Cyclobutyl)Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.