Description

1,3-Dichloro-5-Bromoisoquinoline is a high-value halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable precursor for constructing complex heterocyclic scaffolds with tailored electronic and steric properties. This compound is primarily sought after by pharmaceutical R&D teams and specialty chemical manufacturers for applications in medicinal chemistry, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the creation of advanced fungicides and herbicides, leveraging its halogenated structure for enhanced bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials due to its electron-deficient aromatic core.
• Chemical Biology Probes: Utilized to create tagged molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized isoquinoline backbones.

Basic Information

Product Name	1,3-Dichloro-5-Bromoisoquinoline
CAS No.	1215767-89-7
Molecular Formula	C9H4BrCl2N
Molecular Weight	276.95 g/mol
Synonyms	5-Bromo-1,3-dichloroisoquinoline; 1,3-Dichloro-5-bromoisoquinoline; Isoquinoline, 5-bromo-1,3-dichloro-; 1215767-89-7; 5-Bromo-1,3-dichloro-isoquinoline; 1,3-Dichloro-5-bromo-isoquinoline
EINECS	Contact for details

Quality Control

Our 1,3-Dichloro-5-Bromoisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.