Description

4-Bromo-8-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and chlorine substituents, makes it an invaluable intermediate for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactivity of its halogen atoms.
• Academic & R&D: Employed in universities and corporate R&D labs for methodological studies and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-8-Chloroisoquinoline
CAS No.	1215767-86-4
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	8-Chloro-4-bromoisoquinoline; 4-Bromo-8-chloro-isoquinoline; Isoquinoline, 4-bromo-8-chloro-; 1215767-86-4
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-8-Chloroisoquinoline is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment is to supply material that meets the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.