Description

2-Propenyl-(Propyl-D7)-Propanedioic Acid Diethyl Ester is a deuterium-labeled derivative of a malonic acid ester, a crucial building block in organic synthesis. This compound matters for its role as a stable isotope-labeled internal standard, enabling precise quantification and metabolic pathway tracing in advanced analytical chemistry. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for applications requiring high specificity and accuracy, such as drug metabolism and pharmacokinetics (DMPK) studies.

Application

• Internal Standard for Mass Spectrometry: Used as a deuterated standard for the accurate quantification of its non-labeled counterpart or related metabolites in LC-MS and GC-MS analysis.
• Pharmaceutical Research: Critical in drug discovery and development for conducting stable isotope labeling studies to investigate drug metabolism, bioavailability, and pharmacokinetic profiles.
• Metabolomics and Biomarker Discovery: Facilitates precise tracking of biochemical pathways and the identification of biomarkers in complex biological samples.
• Synthetic Intermediate: Serves as a specialized, labeled building block for the synthesis of more complex deuterated molecules for research purposes.
• Agrochemical Development: Employed in environmental fate studies and residue analysis of pesticides and herbicides.
• Academic Research: Utilized in universities and research institutes for mechanistic studies in organic chemistry and biochemistry.

Basic Information

Product Name	2-Propenyl-(Propyl-D7)-Propanedioic Acid Diethyl Ester
CAS No.	1215738-07-0
Molecular Formula	C11H9D7O4
Molecular Weight	~215.28 g/mol
Synonyms	Diethyl 2-(2-Propenyl)(propyl-d7)malonate; (Propyl-d7)allylmalonic Acid Diethyl Ester; Deuterated Allylpropylmalonate Diethyl Ester; Diethyl (Allyl)(propyl-d7)propanedioate; 2-Allyl-2-(propyl-d7)malonic Acid Diethyl Ester; D7-Labeled Malonate Ester; CAS 1215738-07-0
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is characterized using advanced analytical techniques including NMR (¹H, ¹³C), Mass Spectrometry, and HPLC. Certificates of Analysis (COA) are provided, detailing parameters such as chemical purity (typically ≥95% by HPLC), isotopic purity (≥98 atom % D), and identity confirmation. We adhere to relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.