Description

2-[4-(3-Benzo[B][1]Benzazepin-11-Ylpropyl)Piperazin-1-Yl]-1,1,2,2-Tetradeuterioethanol is a deuterated derivative of a benzazepine-piperazine ethanol compound, offering enhanced metabolic stability and pharmacokinetic properties for advanced research. This high-purity labeled compound is critical for applications requiring precise tracking and analysis in complex biological systems. It is primarily utilized by pharmaceutical R&D teams and analytical laboratories engaged in drug discovery, metabolism studies, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quality control and validation of analytical methods in drug development.
• Deuterated API Synthesis: Used as a key intermediate or building block in the synthesis of deuterium-labeled pharmaceutical compounds.
• Metabolic Pathway Tracing: Enables detailed studies of drug metabolism and pharmacokinetics (DMPK) due to its isotopic label.
• Biochemical Research: Employed in receptor binding assays and other in-vitro studies to investigate biological activity.
• Mass Spectrometry Internal Standard: Acts as a stable isotope-labeled internal standard for precise quantitative analysis via LC-MS/MS.
• Neuroscience Research: Investigated for potential activity in central nervous system (CNS) related pathways, given its structural class.

Basic Information

Product Name	2-[4-(3-Benzo[B][1]Benzazepin-11-Ylpropyl)Piperazin-1-Yl]-1,1,2,2-Tetradeuterioethanol
CAS No.	1215716-70-3
Molecular Formula	C25H29D4N3O
Molecular Weight	Contact for details
Synonyms	11-[3-[4-(2-Hydroxy-1,1,2,2-d4-ethyl)piperazin-1-yl]propyl]-5H-dibenzo[b,e][1,4]diazepine; Deuterated Aripiprazole Metabolite Derivative; 1,1,2,2-Tetradeutero-2-[4-[3-(5H-Dibenzo[b,e][1,4]diazepin-11-yl)propyl]-1-piperazinyl]ethanol; 2-[4-[3-(Dibenzo[b,e][1,4]diazepin-11-yl)propyl]piperazin-1-yl]ethanol-d4; Aripiprazole-d4 Metabolite Analog; OPC-14597 derivative-d4
EINECS	Contact for details

Quality Control

Our 2-[4-(3-Benzo[B][1]Benzazepin-11-Ylpropyl)Piperazin-1-Yl]-1,1,2,2-Tetradeuterioethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isotopic enrichment analysis, to ensure compliance with exacting standards for research chemicals. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and isotopic purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.