Description

5,5-Dideuterio-3-(3,5-Dichloro-2,4,6-Trideuteriophenyl)-2,4-Dioxo-n-Propan-2-Ylimidazolidine-1-Carboxamide is a deuterated derivative of a hydantoin-based compound, designed for advanced research and development applications. This high-value specialty chemical is critical for studies requiring isotopic labeling, such as metabolic pathway tracing and pharmacokinetic analysis. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and academic institutions focused on developing novel therapeutic agents and sophisticated analytical methods.

Application

• Pharmaceutical Research & Development: Serves as a deuterium-labeled internal standard or reference compound in quantitative bioanalytical methods like LC-MS/MS for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Used in isotopic labeling experiments to track the fate and transformation of molecules within biological systems, providing insights into metabolic routes.
• Analytical Chemistry Standards: Employed as a high-purity certified reference material (CRM) to ensure accuracy and precision in mass spectrometry and other spectroscopic analyses.
• Mechanistic Studies: Facilitates the investigation of chemical and enzymatic reaction mechanisms by leveraging kinetic isotope effects (KIE) due to the deuterium atoms.
• Process Chemistry & Impurity Profiling: Acts as a marker or tracer in process development and for identifying and quantifying process-related impurities in active pharmaceutical ingredients (APIs).
• Stable Isotope Labeled Compound Synthesis: Functions as a key intermediate or building block in the multi-step synthesis of more complex deuterated molecules for research.

Basic Information

Product Name	5,5-Dideuterio-3-(3,5-Dichloro-2,4,6-Trideuteriophenyl)-2,4-Dioxo-n-Propan-2-Ylimidazolidine-1-Carboxamide
CAS No.	1215631-57-4
Molecular Formula	C13H9D5Cl2N3O3
Molecular Weight	342.22 g/mol (for predominant isotopologue)
Synonyms	Deuterated Hydantoin Derivative; 5,5-Dideutero-3-(3,5-dichloro-2,4,6-trideuteriophenyl)-2,4-dioxo-1-(propan-2-yl)imidazolidine-1-carboxamide; 1-Carbamoyl-5,5-dideutero-3-(3,5-dichloro-2,4,6-trideuteriophenyl)imidazolidine-2,4-dione; Isotopically Labeled Hydantoin; [D5]-Labeled Hydantoin Carboxamide; CAS 1215631-57-4; Deuterium Labeled Internal Standard 1215631-57-4
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality control protocols to ensure isotopic purity, chemical purity, and batch-to-batch consistency essential for research integrity. Each batch is characterized using advanced analytical techniques including NMR (¹H, ¹³C, ²H), High-Resolution Mass Spectrometry (HRMS), and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D%), chemical purity, and identification data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and analytical performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D (by ²H NMR or MS)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.