Description

5-Aminopentanoic Acid Methyl Ester Hydrochloride-D4 is a high-purity, deuterium-labeled derivative of 5-aminopentanoic acid methyl ester hydrochloride, serving as a critical internal standard and analytical tool. This stable isotope-labeled compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by researchers and manufacturers in pharmaceutical development, clinical diagnostics, and advanced biochemical research.

Application

• Quantitative Mass Spectrometry: Serves as a stable isotope-labeled internal standard for the precise quantification of the non-deuterated parent compound and related metabolites in complex biological matrices.
• Pharmacokinetic and Metabolic Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Pharmaceutical Impurity Profiling: Used in method development and validation to identify and quantify process-related impurities and degradation products in active pharmaceutical ingredients (APIs).
• Biomarker Discovery and Validation: Facilitates the accurate measurement of endogenous compounds in biomarker research for various disease states.
• Synthetic Intermediate: Acts as a deuterated building block for the synthesis of more complex labeled compounds for research purposes.
• Quality Control in GMP Environments: Supports analytical method validation and quality control procedures in regulated pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	5-Aminopentanoic Acid Methyl Ester Hydrochloride-D4
CAS No.	1215370-80-1
Molecular Formula	C6H9D4ClNO2
Molecular Weight	163.65 g/mol (for monoisotopic mass)
Synonyms	5-Amino-1-pentanoic Acid Methyl Ester Hydrochloride-D4; Methyl 5-Aminopentanoate Hydrochloride-D4; Methyl 5-Aminovalerate Hydrochloride-D4; δ-Aminovaleric Acid Methyl Ester Hydrochloride-D4; 5-Aminopentanoic Acid Methyl Ester-d4 Hydrochloride; Methyl 5-Aminopentanoate-d4 HCl; [2H4]-Methyl 5-aminopentanoate hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Aminopentanoic Acid Methyl Ester Hydrochloride-D4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.