Description

2-Amino-3-Methyl-3H-Imidazo[4,5-F]Quinoxaline-D3 is a deuterium-labeled analog of a heterocyclic aromatic amine, specifically designed for use as an internal standard in advanced analytical chemistry. This high-purity compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in metabolomics, pharmacokinetic studies, and the detection of trace-level biomarkers.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for precise quantification in LC-MS/MS and GC-MS analyses, correcting for instrument variability and sample preparation losses.
• Biomedical and Pharmaceutical Research: Used in the study of heterocyclic aromatic amine (HAA) metabolism, toxicology, and carcinogenicity.
• Food Safety and Environmental Analysis: Enables accurate monitoring of mutagenic HAAs in cooked food products and environmental samples.
• Metabolomics and Biomarker Discovery: Facilitates the identification and quantification of amine-related metabolites in complex biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as a stable isotope-labeled tracer in ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Reference Material for Method Development: Provides a definitive standard for validating new analytical methods in regulatory and quality control settings.

Basic Information

Product Name	2-Amino-3-Methyl-3H-Imidazo[4,5-F]Quinoxaline-D3
CAS No.	1215363-28-2
Molecular Formula	C10H6D3N5
Molecular Weight	188.21 g/mol
Synonyms	2-Amino-3-methylimidazo[4,5-f]quinoxaline-d3; MeIQx-d3; 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-d3 (common name for non-deuterated form); 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline (deuterated); Deuterated MeIQx; [2,4,8-2H3]-2-Amino-3-methylimidazo[4,5-f]quinoxaline; Internal Standard MeIQx-d3; HAAs-d3.
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Methyl-3H-Imidazo[4,5-F]Quinoxaline-D3 is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Comprehensive testing includes assay by HPLC, confirmation of deuterium incorporation by NMR and MS, and control of related substances. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic purity, and all relevant analytical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Incorporation)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.