Description

1-Methyl-5-Oxo-4,5,6,7-Tetrahydro-1H-Indazole-3-Carboxylic Acid (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate with a distinct fused indazole-carboxylic acid structure. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers developing new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Used in the research and production of potential kinase inhibitors due to its privileged heterocyclic core structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Synthesis: The carboxylic acid functionality allows for further derivatization, making it suitable for creating chemical probes or conjugates for biological studies.

Basic Information

Product Name	1-Methyl-5-Oxo-4,5,6,7-Tetrahydro-1H-Indazole-3-Carboxylic Acid (Saltdata: Free)
CAS No.	1215295-93-4
Molecular Formula	C9H10N2O3
Molecular Weight	194.19 g/mol
Synonyms	1-Methyl-5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid; 1-Methyl-4,5,6,7-tetrahydro-5-oxo-1H-indazole-3-carboxylic acid; 3-Carboxy-1-methyl-4,5,6,7-tetrahydro-5-oxoindazole; 1-Methyl-5-oxo-4,7-dihydro-1H-indazole-3-carboxylic acid; 1215295-93-4; Free acid of 1-Methyl-5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-Oxo-4,5,6,7-Tetrahydro-1H-Indazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.