Description

4-Bromo-6-(Trifluoromethyl)Benzo[D]Thiazole-2-Thiol is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or requiring a benzothiazole core.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the thiazole ring.
• Material Science Research: Acts as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport molecules.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis due to the presence of sulfur and nitrogen donor atoms.
• Chemical Biology Probes: Utilized in the design of fluorescent probes or activity-based protein profiling (ABPP) agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CMOs (Contract Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-Bromo-6-(Trifluoromethyl)Benzo[D]Thiazole-2-Thiol
CAS No.	1215205-88-1
Molecular Formula	C8H3BrF3NS2
Molecular Weight	314.15 g/mol
Synonyms	2-Mercapto-4-bromo-6-(trifluoromethyl)benzothiazole; 4-Bromo-6-(trifluoromethyl)-1,3-benzothiazole-2-thiol; 4-Bromo-6-(trifluoromethyl)-2-benzothiazolethiol; 2-Benzothiazolethiol, 4-bromo-6-(trifluoromethyl)-; 4-Bromo-6-trifluoromethylbenzothiazole-2-thiol; BTBTT
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-(Trifluoromethyl)Benzo[D]Thiazole-2-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.