Description

2-Arachidonyl Glycerol-D5 is a deuterated analog of the primary endogenous ligand for the cannabinoid receptors CB1 and CB2. This stable isotope-labeled compound is essential for high-precision analytical research, providing an internal standard for accurate quantification in complex biological matrices. It is a critical tool for researchers and analytical laboratories in the pharmaceutical, biotechnology, and life science sectors conducting metabolic studies, pharmacokinetic research, and endocannabinoid system analysis.

Application

• Internal Standard for Mass Spectrometry (LC-MS/MS, GC-MS): Used for the precise quantification of endogenous 2-AG in biological samples like plasma, serum, and tissue homogenates.
• Metabolic Pathway Research: Facilitates the study of the biosynthesis and degradation pathways of the endocannabinoid system.
• Pharmacokinetic and Bioanalytical Studies: Enables accurate measurement of drug effects on endocannabinoid levels in preclinical and clinical research.
• Neuroscience and Neuropharmacology: Supports investigations into the role of endocannabinoids in neurological functions and disorders.
• Quality Control Reference Material: Serves as a certified reference standard for assay validation and quality control in analytical laboratories.

Basic Information

Product Name	2-Arachidonyl Glycerol-D5
CAS No.	1215168-37-8
Molecular Formula	C₂₃H₃₃D₅O₄
Molecular Weight	383.58 g/mol
Synonyms	2-AG-D5; 2-Arachidonoylglycerol-D5; 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoyl]-1,3-propanediol-d5; 1,3-Dihydroxy-2-propanyl (5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenoate-d5; Deuterated 2-AG; 2-AG Internal Standard; 2-AG-d5; 2-Arachidonoyl-rac-glycerol-d5
EINECS	Contact for details

Quality Control

Our 2-Arachidonyl Glycerol-D5 is manufactured under strict quality control protocols to ensure the highest standards of isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic methods. We support compliance with GMP and ISO 17034 guidelines for reference material producers.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and ensure long-term stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.