Description

6-Bromo-3-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and other therapeutic areas. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted small molecule drugs.
• Drug Discovery Research: Used in medicinal chemistry for the design and construction of new chemical entities with potential biological activity.
• API Synthesis: Serves as a core scaffold or a functionalized fragment in the production of complex final Active Pharmaceutical Ingredients.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Process Chemistry Development: Employed in route scouting and optimization studies for scalable and efficient manufacturing processes.
• Custom Synthesis: A starting material for the preparation of specialized derivatives and analogs for client-specific research programs.

Basic Information

Product Name	6-Bromo-3-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole
CAS No.	1214900-50-1
Molecular Formula	C13H15BrN2O
Molecular Weight	295.18 g/mol
Synonyms	6-Bromo-3-methyl-1-(oxan-2-yl)-1H-indazole; 6-Bromo-3-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1H-Indazole, 6-bromo-3-methyl-1-(tetrahydro-2H-pyran-2-yl)-; 6-Bromo-3-methyl-1-(tetrahydropyran-2-yl)indazole; 6-Bromo-3-methyl-1-(2-tetrahydropyranyl)-1H-indazole; THP-protected 6-bromo-3-methylindazole; 6-Br-3-Me-1-THP-indazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.