Description

6-Iodo-3,3-Dimethyl-1,3-Dihydro-Indol-2-One is a high-value halogenated oxindole derivative, a crucial building block in modern organic synthesis. Its unique structure, featuring a reactive iodine atom on an aromatic ring, makes it indispensable for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Research: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the oxindole scaffold into complex molecular architectures.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	6-Iodo-3,3-Dimethyl-1,3-Dihydro-Indol-2-One
CAS No.	1214900-47-6
Molecular Formula	C10H10INO
Molecular Weight	287.10 g/mol
Synonyms	6-Iodo-3,3-dimethylindolin-2-one; 3,3-Dimethyl-6-iodoindolin-2-one; 6-Iodo-3,3-dimethyl-2-indolinone; 1,3-Dihydro-6-iodo-3,3-dimethyl-2H-indol-2-one; 6-Iodo-3,3-dimethyloxindole; 6-Iodo-3,3-dimethyl-1,3-dihydro-2H-indol-2-one; 6-Iodo-3,3-dimethyl-2-oxindole
EINECS	Contact for details

Quality Control

Our 6-Iodo-3,3-Dimethyl-1,3-Dihydro-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.