Description

6,7-Diethoxy-3,4-Dihydro-1H-Isoquinoline-1,2-Dicarboxylic Acid 2-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific isoquinoline-based molecular scaffold. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel therapeutic agents, where consistent quality and reliable supply are critical.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially alkaloid-derived molecules.
• API Synthesis: Used in the construction of the core isoquinoline structure for potential APIs in neurological and cardiovascular research.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in route development and pilot-scale manufacturing for clinical trial material supply.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.
• Academic Research: Used in synthetic organic chemistry studies focused on heterocyclic compound synthesis and functionalization.

Basic Information

Product Name	6,7-Diethoxy-3,4-Dihydro-1H-Isoquinoline-1,2-Dicarboxylic Acid 2-tert-Butyl Ester
CAS No.	1214645-14-3
Molecular Formula	C19H25NO6
Molecular Weight	363.41 g/mol
Synonyms	1,2,3,4-Tetrahydro-6,7-diethoxyisoquinoline-1,2-dicarboxylic acid 2-tert-butyl ester; 2-(tert-Butyl) 1-methyl 6,7-diethoxy-3,4-dihydro-1H-isoquinoline-1,2-dicarboxylate; 6,7-Diethoxy-1,2,3,4-tetrahydroisoquinoline-1,2-dicarboxylic acid 2-tert-butyl ester; tert-Butyl 6,7-diethoxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylate-2-carboxylate; 1214645-14-3; 6,7-Diethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester (related structure); DIETHOXY DIHYDRO ISOQUINOLINE DICARBOXYLATE T-BUTYL ESTER
EINECS	Contact for details

Quality Control

Our 6,7-Diethoxy-3,4-Dihydro-1H-Isoquinoline-1,2-Dicarboxylic Acid 2-tert-Butyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.