Description

5-((4S)-2-Oxohexahydro-1H-Thieno[3,4-D]Imidazol-4-Yl)Pentanehydrazide is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry, essential for the synthesis of complex bioactive molecules. Its value lies in its role as a critical building block for research and development in modern medicinal chemistry, enabling the creation of novel therapeutic agents. This compound is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on developing new drugs, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: The hydrazide functional group enables its use in the synthesis of chemical probes, diagnostic agents, and targeted drug conjugates.
• Peptidomimetic Synthesis: Used in the construction of peptidomimetics and constrained peptide analogs due to its fused bicyclic imidazolidinone-thiophene core.
• Catalyst & Ligand Preparation: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	5-((4S)-2-Oxohexahydro-1H-Thieno[3,4-D]Imidazol-4-Yl)Pentanehydrazide
CAS No.	1214641-84-5
Molecular Formula	C12H20N4O2S
Molecular Weight	284.38 g/mol
Synonyms	(4S)-4-(5-Hydrazinyl-5-oxopentyl)hexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one; 5-[(4S)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide; (S)-5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanehydrazide; Biotin Hydrazide Analog; Thienoimidazolidone Pentanehydrazide; Stereoisomer of Biotin-derived Hydrazide; CAS 1214641-84-5
EINECS	Contact for details

Quality Control

Our 5-((4S)-2-Oxohexahydro-1H-Thieno[3,4-D]Imidazol-4-Yl)Pentanehydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (4S isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.