Description

4-Bromo-2-Bromomethyl-1-Trifluoromethylbenzene is a high-value, multi-functional halogenated aromatic building block, distinguished by its reactive bromomethyl and bromo substituents on a trifluoromethylbenzene core. This compound is critical for advanced organic synthesis, enabling the precise introduction of functional groups and fluorinated motifs into target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl and bromine groups contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in catalysis, especially in cross-coupling reactions prevalent in modern organic chemistry.
• Advanced Material Precursor: Employed in the research and development of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties imparted by fluorine and bromine atoms.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems, leveraging the reactivity of the bromomethyl group for bioconjugation.

Basic Information

Product Name	4-Bromo-2-Bromomethyl-1-Trifluoromethylbenzene
CAS No.	1214327-32-8
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	1-Bromo-4-(bromomethyl)-2-(trifluoromethyl)benzene; 2-Bromomethyl-4-bromo-alpha,alpha,α-trifluorotoluene; alpha,alpha,α-Trifluoro-2-bromomethyl-4-bromotoluene; 4-Bromo-2-(bromomethyl)benzotrifluoride; 2,4-Dibromo-alpha,alpha,α-trifluorotoluene (Note: verify specific isomer); Benzene, 1-bromo-4-(bromomethyl)-2-(trifluoromethyl)-; BTB (abbreviation in research contexts)
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Bromomethyl-1-Trifluoromethylbenzene is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including purity (typically by GC or HPLC), identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.