Description

3-Amino-5-Chloro-1,3-Dihydro-2H-Indol-2-One Hydrochloride is a high-purity, synthetically valuable indole derivative used as a critical building block in advanced organic synthesis. Its primary value lies in its functionalized indole core, which serves as a versatile intermediate for constructing complex molecules with potential biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing novel heterocyclic compounds for therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the indole scaffold for enhanced efficacy.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic libraries for high-throughput screening and medicinal chemistry programs.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors and functional dyes due to its electron-rich indole structure.

Basic Information

Product Name	3-Amino-5-Chloro-1,3-Dihydro-2H-Indol-2-One Hydrochloride
CAS No.	1214187-61-7
Molecular Formula	C8H8ClN2O·HCl
Molecular Weight	221.08 g/mol
Synonyms	5-Chloro-3-aminooxindole hydrochloride; 3-Amino-5-chlorooxindole hydrochloride; 5-Chloro-3-amino-1,3-dihydro-2H-indol-2-one hydrochloride; 3-Amino-5-chloro-2-oxindole hydrochloride; 2-Oxo-3-amino-5-chloroindoline hydrochloride; 5-Chloro-3-aminoindolin-2-one hydrochloride; 3-Amino-5-chloro-1H-indol-2(3H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Chloro-1,3-Dihydro-2H-Indol-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.